Fluoride Ion Release Characteristics of Fluoride-Containing Varnishes—An In Vitro Study

Despite the latest advances in orthodontic treatment, white spot lesions remain a common side effect of fixed appliance therapy. An effective treatment for prevention is use fluoride-containing products. The aim present vitro study was to check durability tested products their fluoride release into surrounding solution. Three varnishes (Protecto CaF2 Nano one-step seal, Bifluorid 12 single dose, and Fluor Protector S) were applied hydroxyapatite discs kept diluted Total Ionic Strength Adjustment Buffer III (TISAB III) solution ion measurement. A group clear served as control group. carrier (N = 40) underwent three thermal cycling runs 20 days. Before first run after each run, concentration measured at appointed times (T) T0, T1, T2, T3. Fluoride highest T1 all (median values Protecto seal: 0.09 ppm, dose: 37.67 S: 3.36 ppm) except group, showing its peak T0 (0.04 ppm). There significant difference between measurement times. achieved significantly higher than other (p < 0.05 times). solitary product application only once or twice per year, stated by manufacturers, cannot be supported.